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KMID : 0988920180160030445
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Intestinal Research
2018 Volume.16 No. 3 p.445 ~ p.457
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Magnetic resonance enterography predicts the prognosis of Crohn’s disease
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Lee Ji-Hoon
Park Yong-Eun
Seo Ni-Eun
Lee Hyun-Jung
Park Soo-Jung
Kim Tae-Il
Kim Won-Ho
Lim Joon-Seok
Cheon Jae-Hee
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Abstract
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Background/Aims: Magnetic resonance enterography (MRE) has emerged as an important tool in the diagnosis and follow-up of Crohn’s disease (CD). The aim of this study was to evaluate whether MRE findings could predict the prognosis of CD.
Methods: In this retrospective study, a total of 173 patients with clinical remission of CD (n=61) or active CD (n=112) were identified. The outcomes of clinical relapse, admission, surgery, and need for other medications according to the MRE findings were evaluated.
Results: The presence of active inflammation on MRE was observed in 93 (83%) patients with clinically active CD and in 44 (72.1%) patients with clinical remission of CD, without a statistically significant difference (P=0.091). In multivariate analysis, active inflammation on MRE increased the risk for clinical relapse (hazard ratio [HR], 6.985; 95% confidence interval [CI], 1.024?47.649) in patients with clinical remission of CD. In patients with clinically active CD, active inflammation on MRE increased the risk for CD-related hospitalization (HR, 2.970; 95% CI, 1.006?8.772).
Conclusions: The presence of active inflammation on MRE was significantly associated with poor prognosis both in patients with clinical remission of CD and in those with active CD.
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KEYWORD
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Magnetic resonance enterography, Prognosis, Crohn disease
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